It is the first analysis of the effects of both stimulants and A2As in preschool children. Results of this ADHD/A2A study are published in JAMA. Just as important, the study shows that these medications have fewer side effects than stimulants, like methylphenidate (Ritalin, Concerta) and amphetamines (Adderall, Vyvanse), which are often the first line of ADHD treatment.Ī2As were initially used to regulate blood pressure in adults but then gained FDA approval to treat ADHD in school-aged children after clinical trials found they could improve attention and focus and reduce ADHD symptoms. But what if symptoms linger, or are so severe that they interfere with a child’s social, emotional, and educational development?Ī study from Boston Children’s Hospital finds that starting drug treatment with alpha-2-adrenergic agonists (A2As), such as guanfacine and clonidine, can be effective in reducing ADHD symptoms in preschool-age children. For these children, behavioral interventions intended to redirect a child or otherwise replace negative behaviors with positive ones are the first line of treatment. (Image: Adobe Stock/Illustration: Sebastian Stankiewicz, Boston Children's)Ībout 2.4 percent of preschool-age children have an attention-deficit/hyperactivity disorder (ADHD) diagnosis. ![]() ![]() ![]() A study comparing two types of ADHD medications in preschool-age children shows alpha-2-adrenergic agonists like guanfacine and clonidine are effective in reducing ADHD symptoms but with a lower rate of side effects.
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